General Clinical Chemistry Analyzers and Accessories
Abcam GLPG-1690, 25MG
MW 588.7 Da, Purity >=98%. Selective autotaxin inhibitor with potential application in idiopathic pulmonary disease (IPF).
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB742457 (Intepirdine), 5-HT6 antagonist, 5MG
MW 353.4 Da. Potent (pKi = 9.63) and highly selective 5-HT6 antagonist. Greater thsan 100-fold selective against other receptors. Reverses learning impairment in animal models.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Fluorescein di-ß-D-glucuronide, dimethyl ester, 2MG
MW 712.61 g/mol, Purity >95%. Sensitive, cell-permeant β-glucuronidase substrate for live cell and tissue assays of cloned GUS marker gene activity and transfection levels.
The product is subject to the following: Abcam Restricted Use Statement
Abcam CCG 1423, Rho pathway-mediated signaling inhibitor, 5MG
MW 454.7 Da, Purity >98%. Specific inhibitor of Rho pathway-mediated signaling and activation of serum response factor (SRF) transcription. Displays activity in several in vitro cancer cell functional assays. Potently (<1 mumol/L) inhibits lysophosphatidic acid-induced DNA synthesis in PC-3 prostate cancer cells, inhibits growth of RhoC-overexpressing melanoma lines at nanomolar concentrations. Selectively stimulates apoptosis of the metastasis-prone, RhoC-overexpressing melanoma cell lines. Acts at or downstream of MLK1 and upstream of SRF. Blocks MLK1 nuclear localization.
The product is subject to the following: Abcam Restricted Use Statement
Abcam LMK 235, HDAC inhibitor, 25MG
MW 294.35 Da, Purity >98%. Highly potent and selective HDAC inhibitor. Greater potency for HDAC4 and HDAC5 (IC₅₀ = 11.9 and 4.2 nM, respectively) than other HDAC family members (IC₅₀ values = HDAC1 320 nM, HDAC2 881 nM, HDAC6 55.7 nM, and HDAC8 1278 nM. Demonstrates inhibitor activity in human ovarian cell lines (IC₅₀ =0.49μM) and cisplatin resistant cell lines (IC₅₀ = 0.32μM).
The product is subject to the following: Abcam Restricted Use Statement
Abcam STING Inhibitor, C-176, 25MG
MW 358.09 Da, Purity >=98%. STING inhibitor C-176 is a potent, small-molecule inhibitor of STING (stimulator of interferon genes) protein, that attenuates STING-associated autoinflammatory disease in mice. STING protein is a central signaling component of the intracellular DNA sensing pathway.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Sunitinib, Free base, 100MG
MW 398.5 Da, Purity >=99%. Sunitinib is a free base form of Sunitinib malate. A CSF-1 receptor kinase inhibitor .
The product is subject to the following: Abcam Restricted Use Statement
Hach Company CLT10sc Total CL Analyzer w/pH
CLT10sc Total Chlorine Analyzer with pHD Differential SensorIncludes CL10 sc Panel-1 m digital extension cable-Panel Manual-pHD Sensor Manual-Chlorine Sensor Manual
Abcam IWP-4, 10MG
MW 496.6 Da, Purity >98%. Potent inhibitor of Wnt pathway regulatory protein porupine (Porcn). Blocks Wnt protein secretion and prevents the canonical and non-canonical signaling pathways. Blocks palmitylation, and subsquent secretion and activity of Wnt. Induces differentiation of cardiomyocytes from human ESCs and iPSCs.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Vistusertib (AZD2014), 5MG
MW 462.5 Da, Purity >98%. Novel potent and selective mammalian rapamycin (mTOR) inhibitor (IC₅₀ = 2.8 nM). Highly selective against multiple PI3K isoforms. Also targets P-Akt (IC₅₀ = 80 nM) and pS6 (IC₅₀ = 200 nM). An oral inhibitor with potential anti-neoplastic activity.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Elevenostat, 1MG
MW 315.32 g/mol, Purity >=95%. A small molecule hydroxamic acid derivative that acts as a HDAC11-selective inhibitor. Reporter assays using a luciferase-linked Foxp3 promoter shows that HDAC11 decreases the signal driven by NFκB/p65, alone or in the presence of transfected Foxp3, and impairs luciferase activity driven by p65, Foxp3 and the HAT enzyme, p300. The inhibitory effects of HDAC11 at the Foxp3 promoter are reversed by Elevenostat (JB3-22), (IC₅₀ 0.235 μM). Elevenostat also partially reverses the inhibitory effect of HDAC11 on p300-induced Foxp3 acetylation at lysine 31 consistent with the ability of HDAC11 to directly regulate acetylation of Foxp3.
The product is subject to the following: Abcam Restricted Use Statement
Abcam FC 131, C x CR4 activation inhibitor, 1MG
MW 729.8 Da, Purity >95%. FC 131, CXCR4 activation inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Ryuvidine, 1MG
MW 284.3 Da, Purity >98%. Inhibits (IC₅₀ = 500 nM) KMT5A / SETD8 / Pr-SET7 and suppresses H4JK20 monomethylation in vitro. Weakly active against Cdk4 (IC₅₀ = 6 μM). Induces S-phase accumulation in HEK-293 cells. Cytotoxic towards a number of human cancer cell lines. May induce the DNA damage response.
The product is subject to the following: Abcam Restricted Use Statement
Abcam WH-4-023, 5MG
MW 568.7 Da, Purity >98%. Potent and selective inihbitor of the tyrosine kinases Lck and Src with IC₅₀ values of 2 nM for Lck and 6 nM for Src.
The product is subject to the following: Abcam Restricted Use Statement